Gene interactions and pathways from curated databases and text-mining

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CD4 — PTK6

Text-mined interactions from Literome

Ledbetter et al., Semin Immunol 1990 : CD4 therefore regulates protein tyrosine kinase activation by specific interaction with CD3/Ti, whereas immobilized anti-CD3 may differ from anti-CD3 in solution in the activation of protein tyrosine phosphatase ( s ) such as CD45
Phipps et al., AIDS 1996 : The role of the gp120-CD4-Lck interaction in HIV related PTK activation was determined using gp 120 treated Jurkat cells and HIV-infection of JCaM 1.6 cells, a Jurkat derived cell line that lacks p56lck