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CCND1 — LEF1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Jesse et al., Int J Cancer 2010
(Carcinoma, Pancreatic Ductal...) :
Expression of
Lef-1 FL, but not the newly identified Lef-1 Deltaexon VI,
induced the expression of the cell cycle regulating proteins c-myc and
cyclin D1 in cooperation with beta-catenin and it enhanced cell proliferation
Shelton et al., PloS one 2012
(Adenocarcinoma...) :
We found that during gland development
cyclin D1 is elevated and localized to the gland buds, and that this
requires the presence of
Lef1