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DUSP4 — KRAS

Text-mined interactions from Literome

Gaedcke et al., Genes Chromosomes Cancer 2010 (Rectal Neoplasms) : Mutated KRAS results in overexpression of DUSP4 , a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
Cagnol et al., Oncogene 2013 (Cell Transformation, Neoplastic...) : Oncogenic KRAS and BRAF activation of the MEK/ERK signaling pathway promotes expression of dual-specificity phosphatase 4 ( DUSP4/MKP2 ) resulting in nuclear ERK1/2 inhibition