Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Olszyna et al., J Infect Dis 2000 (Endotoxemia) : Sixteen healthy subjects were intravenously injected with lipopolysaccharide (LPS), once with placebo and once with recombinant human interleukin (IL)-10 ( 25 microgram/kg ), to determine the effect of IL-10 on LPS induced production of macrophage inflammatory protein (MIP)-1alpha, MIP-1beta , and monocyte chemoattractant protein (MCP)-1 ... Pretreatment with IL-10 inhibited LPS induced release of MIP-1alpha, MIP-1beta , and MCP-1
Zaitseva et al., Infect Immun 2001 : Both HBa and LPS-Ba stimulated high levels of MIP-1alpha and MIP-1beta production in elutriated monocytes and even higher levels in macrophages
Spek et al., J Clin Immunol 2003 : LPS induced MIP-1alpha, MIP-1beta , IL-8, IL-1beta, and IL-1Ra mRNA production, which was delayed by 1 hr and reduced twofold by IC14 treatment
Jing et al., J Leukoc Biol 2003 : Intraperitoneal administration of PGE2 together with LPS results in a reduction in the levels of CCL3 and CCL4 released in the peritoneal fluid, a reduction in the number of dendritic cells accumulating in the peritoneal cavity, and a reduction in CCL3 amount per cell in the peritoneal cell population
Lu et al., Invest Ophthalmol Vis Sci 2006 : Dexamethasone also inhibited LPS induced MIP-1beta release, whereas triptolide did not
Lakshmanan et al., J Immunol 2007 : Because a specific NF-kappaB inhibitor blocked LPS induced IL-8 and CCL4 mRNA expression as well as IL-8 and CCL4 secretion in THP1 cells, we investigated the role of caspase-4 in NF-kappaB signaling
Minami et al., J Biol Chem 2008 (Atherosclerosis) : Additionally, EPRAP knockdown as well as deficiency of NF-kappaB1 in macrophages attenuates the inhibitory effect of PGE ( 2 ) on LPS induced MIP-1beta production
Tamassia et al., Int Immunol 2008 (Sepsis...) : Consistent with the presence of a fully functional IL-10R, modulation of LPS induced CXCL8, CCL4 , tumour necrosis factor-alpha and IL-1ra gene expression was also rapidly induced by IL-10 in septic, but not normal, neutrophils
Martin et al., Cell Immunol 1991 : In contrast, PGE1 inhibits LPS induced JE, MIP-1 alpha, and MIP-1 beta mRNA expression and this inhibition is partially dependent on a cAMP mediated pathway of signal transduction
Chung et al., Mol Cells 2009 : These results indicate that A. actinomycetemcomitans LPS stimulates the several chemokines expressions ( MIP-1alpha, MIP-1beta , MIP-1gamma, RANTES, MIP-2, and IP 10 ) in Raw 264.7 cells
Buenestado et al., Br J Pharmacol 2012 : Roflumilast and roflumilast N-oxide concentration-dependently reduced the LPS stimulated release of CCL2, CCL3, CCL4 , CXCL10 and TNF-a from human lung macrophages, whereas that of CXCL1 or CXCL8 was not altered
McManus et al., J Immunol 1998 : In response to LPS , TNF-alpha, or IL-1 beta, both MIP-1 alpha and MIP-1 beta were induced at the mRNA and protein levels in a dose- and time dependent manner