Burton et al., Brain Res Mol Brain Res 2002
(Alzheimer Disease...) :
A model of anti-apoptotic APP signaling is proposed where APP mediates p38 MAPK dependent phosphorylation and activation of MEF2
Westra et al., Ann Rheum Dis 2006
(Carcinoma, Hepatocellular...) :
The effects of p38 MAPK inhibition on APP production and mRNA expression in four human hepatoma cell lines was investigated, after stimulation with interleukin (IL)6 and/or IL1beta or tumour necrosis factor alpha
Zhang et al., Biochim Biophys Acta 2013
(Lung Neoplasms...) :
Treatment with NAC reduces AD-1 induced p38 phosphorylation, which indicates that ROS generation is involved in the AD-1 induced p38 activation