Gene interactions and pathways from curated databases and text-mining

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CHRNA7 — PTGS2

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PTGS2 → CHRNA7 (increases, CHRNA7 Activity)
    Evidence: Other pathways underlying nAChR-induced cell proliferation include activation of NF-kB, Src, the 5-lipooxygenase pathway [36], Akt, HIF-1a [37,38] and COX-2 [19,26,33].