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FOXP3 — IL10

Text-mined interactions from Literome

Schaub et al., Respir Res 2006 (Hypersensitivity, Immediate) : Ppg induced IL-10 production and induction of Foxp3 were higher in CBMC without, than with maternal atopy ( p = 0.04, p = 0.049 )
Caudy et al., J Allergy Clin Immunol 2007 (Genetic Diseases, X-Linked...) : These data show that CD25 deficiency results in an IPEX-like syndrome and suggests that although Foxp3 is not required for normal IL-10 expression by human CD4 lymphocytes, CD25 expression is important
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Silva-Campa et al., Virology 2009 (Porcine Reproductive and Respiratory Syndrome) : Analysis of the expressed cytokines suggested that the induction of Foxp3 ( + ) CD25 ( + ) T cells is dependent on TGF-beta but not IL-10
Scholzen et al., PLoS Pathog 2009 (Malaria, Falciparum) : Generation of Foxp3 ( hi ), but not Foxp3 ( int ), cells specifically required TGFbeta1 and IL-10
Unutmaz et al., Nat Immunol 2009 (Colitis) : A report in this issue describes a key role for interleukin 10 produced by lamina propria macrophages in maintaining Foxp3 expression during inflammatory responses in the intestine
Heo et al., Immunol Lett 2010 (Arthritis, Rheumatoid) : IL-10 induced Foxp3 ( + ) regulatory T cells in the human CD4 ( + ) T cell population
Schmitz-Winnenthal et al., Gastroenterology 2010 (Carcinoma...) : Pancreatitis-specific IL-10 responses were mediated by IL-10 ( + ) IFN-gamma ( - ) FoxP3 ( + ) regulatory T cells, which were expanded in the blood, bone marrow, and pancreatitis lesions and possessed the potential to suppress the proliferation of autologous conventional T cells in an antigen-specific manner
Hong et al., J Clin Immunol 2010 (Asthma...) : Importantly, heat killed L. plantarum administration induced Foxp3 expression in intestinal lamina propria cells, and heat killed L. curvatus induced IL-10 as a way of inducing tolerance
Xie et al., Scand J Immunol 2010 : The 4-antibodies approach prevented lymphocytic infiltration in the grafts, inhibited memory T-cells proliferation in the spleen, increased IL-10 secretion in the serum, and enhanced the expression of CD4 ( + ) Foxp3 ( + ) regulatory T cells ( Tregs ) in spleen
Round et al., Proc Natl Acad Sci U S A 2010 (Colitis) : Functional Foxp3 ( + ) Treg cells are also produced by PSA during intestinal inflammation, and Toll-like receptor 2 signaling is required for both Treg induction and IL-10 expression
Haque et al., PLoS Pathog 2010 (Malaria, Cerebral) : Furthermore, Foxp3 ( + ) cell mediated protection was dependent upon CTLA-4 but not IL-10
Huber et al., Immunity 2011 (Colitis...) : Th17 cells express interleukin-10 receptor and are controlled by Foxp3? and Foxp3+ regulatory CD4+ T cells in an interleukin-10 dependent manner
Trandem et al., J Virol 2011 (Acute Disease...) : Additionally, IL-10 increased both the frequency and number of Foxp3 ( + ) regulatory CD4 T cells in the infected central nervous system
Liu et al., J Immunol 2011 (Colonic Neoplasms...) : The suppressive activity of tumor associated Foxp3 ( + ) CD4 ( + ) CD25 ( + ) regulatory T cells ( Treg ) was IL-10 dependent
Vanvalkenburgh et al., J Exp Med 2011 (Inflammatory Bowel Diseases) : These experiments demonstrate that Bcl11b is indispensable for T ( reg ) suppressor function and for maintenance of optimal Foxp3 and IL-10 gene expression, as well as for the induction of Foxp3 expression in conventional CD4 ( + ) T cells in response to Tgf-ß and generation of iT ( reg ) cells
Hartmann et al., J Immunol 2011 (Filariasis) : In contrast, we show that L. sigmodontis induced, host derived IL-10 mediated Foxp3 induction in transferred Th cells and significantly contributed to the observed Th cell hypoproliferation within infected mice
Elliott et al., Ann N Y Acad Sci 2012 (Immune System Diseases...) : Helminth exposure tends to inhibit IFN-? and IL-17 production, promote IL-4, IL-10 , and TGF-ß release, induce CD4 ( + ) T cell Foxp3 expression, and generate regulatory macrophages, dendritic cells, and B cells
van der Vlugt et al., PloS one 2012 (Hypersensitivity...) : Splenic marginal zone CD1d ( + ) B cells proved to be the responsible splenic B cell subset as they produced high levels of IL-10 and induced FoxP3 ( + ) T cells in vitro
Urry et al., Eur J Immunol 2012 (Asthma) : We demonstrate that the enhancement of Foxp3 expression by 1a25VitD3 is impaired by IL-10
Wang et al., Parasitol Int 2013 (Malaria) : In contrast, after DBA/2 was treatment with anti-IL-10R mAb, IL-10R blockade in vivo caused excessive pro-inflammation responses and Foxp3 expression loss on CD4 ( + ) CD25 ( + ) T cells
Reilkoff et al., Am J Respir Crit Care Med 2013 (Disease Models, Animal...) : In comparison to Sema 7a-CD4 ( + ) CD25 ( + ) FoxP3 ( + ) cells, Sema7a ( + ) CD4 ( + ) CD25 ( + ) FoxP3 ( + ) cells exhibit reduced expression of regulatory genes such as IL-10 , and adoptive transfer of these cells induces fibrosis and remodeling in the TGF-ß1 exposed murine lung
Wang et al., Transplantation 2013 (Graft vs Host Disease) : Luciferase reporter assay showed that the expression of IL-10 is directly regulated by Foxp3