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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ADCY3 — IL6

Text-mined interactions from Literome

Kageyama et al., Endocrinology 2003 (MAP Kinase Signaling System) : The adenylate cyclase inhibitor, MDL-12330A, inhibited this Ucn- or Ucn II-induced increase in IL-6 levels
Katz et al., J Cell Physiol 1992 : Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by down regulating parathyroid hormone receptors
Tatsuno et al., Endocrinology 1991 : Neuropeptide regulation of interleukin-6 production from the pituitary : stimulation by pituitary adenylate cyclase activating polypeptide and calcitonin gene related peptide
Carmeliet et al., Neuroendocrinology 1991 : The adenylate cyclase activator forskolin increased IL-6 release in aggregate cultures in the presence of DEX
Manetsch et al., PloS one 2013 : As IL-6 expression ( like MKP-1 ) is cAMP/adenylate cyclase mediated , the long acting ß2-agonist formoterol increased IL-6 mRNA expression and secretion