Gene interactions and pathways from curated databases and text-mining

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ARC — CASP10

Text-mined interactions from Literome

Chen et al., Cancer Res 2008 (Melanoma) : Transfection of cDNA encoding ARC into Me1007 cells inhibited both caspase-8 activation and apoptosis induced by thapsigargin or tunicamycin
Xiao et al., Apoptosis 2011 : Abundance of caspase-inhibitors ( apoptosis repressor with caspase recruitment domain ( ARC ), and heat shock protein ( HSP ) 70 and -25 was significantly higher in myotubes compared to myoblasts, and in addition ARC was suppressed in response to Stsp in myotubes
Koseki et al., Proc Natl Acad Sci U S A 1998 : Further analysis showed that the enzymatic activity of caspase-8 was inhibited by ARC in 293T cells