Gene interactions and pathways from curated databases and text-mining

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VEGFA — WNT3A

Text-mined interactions from Literome

Natsume et al., Cell Biochem Funct 2011 : Wnt3a upregulates transforming growth factor-ß stimulated VEGF synthesis in osteoblasts ... In the present study, we investigated the effect of Wnt3a on TGF-ß stimulated VEGF synthesis in these cells ... Wnt3a , which alone had little effect on the VEGF levels, significantly enhanced the TGF-ß stimulated VEGF release ... These results strongly suggest that Wnt3a upregulates VEGF synthesis stimulated by TGF-ß via activation of the canonical pathway in osteoblasts
Oderup et al., J Immunol 2013 : Wnt3A triggers canonical ß-catenin signaling and preferentially induces DC TGF-ß and VEGF production, whereas Wnt5A induces IL-10 through alternative pathways