Gene interactions and pathways from curated databases and text-mining

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IL2 — ITGA4

Text-mined interactions from Literome

Udagawa et al., J Immunol 1996 : The integrin alpha 4 beta 1 can provide a costimulus to induce IL-2 secretion and IL-2R expression leading to enhanced proliferation of purified, peripheral blood T cells
Itescu et al., Hum Immunol 1998 : IL-2 augmented NK lysis involved interactions between CD2 and CD49d on baboon NK cells and their respective ligands on porcine endothelium, since NK lysis was reduced either by using Mabs against CD2, CD49d, or porcine VCAM, or by treating endothelial cells with PIPLC to cleave GPI linked molecules