Wilkes et al., J Biol Chem 2006
:
Although c-Abl activation by TGF-beta is independent of Smad2 or Smad3, it is prevented by inhibitors of phosphatidylinositol 3-kinase or PAK2
Møller et al., FEBS Lett 2007
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Here we show that ectopic Bcr-Abl expression dramatically increases TGFbeta/Smad dependent transcriptional activity in Cosl cells, and that this may be due to enhancement of Smad promoter activity
Ghosh-Choudhury et al., J Biol Chem 2013
:
Finally, c-Abl associates with BMP receptor IA and regulates phosphorylation of Smad in response to BMP-2