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ABL1 — PDGFRB

Pathways - manually collected, often from reviews:

• NCI Pathway Database PDGFR-beta signaling pathway: c-Abl (ABL1) → PDGF-BB/PDGFRB (dimer) complex (PDGFRB-PDGFB) (modification, activates)
  Srinivasan et al., Cell Signal 2009*
  Evidence: assay

Text-mined interactions from Literome

Plattner et al., Nat Cell Biol 2003 : However, the activity of Src kinases alone is not sufficient for activation of c-Abl by PDGFR ... Here we show that functional phospholipase C-gamma1 ( PLC-gamma1 ) is required for c-Abl activation by PDGFR
Srinivasan et al., Cell Signal 2009 (Glioblastoma) : Importantly, we also show that Abl dependent phosphorylation of PDGFR-beta has functional and biological significances ... Using site directed mutagenesis, we show that Abl dependent phosphorylation of PDGFR-beta activates PDGFR-beta activity, in vitro, but serves to downregulate PDGFR mediated chemotaxis