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FGF7 — MMP1
Text-mined interactions from Literome
Steinberg et al., Development 2005
:
FGF7- and FGF10 mediated morphogenesis is
inhibited by an
MMP inhibitor and a neutralizing antibody to FGF1, suggesting that both FGF1 and MMPs are essential downstream mediators of epithelial morphogenesis
Newberry et al., Mol Endocrinol 1997
:
Ligand activated and constitutively active
FGF receptors
initiate MMP1 induction ... The DNA-protein interactions and signal cascades mediating
FGF induction of the
MMP1 promoter are distinct from two other recently described FGF response elements : the MMP1 promoter ( -123 to -61 ) represents a third FGF activated transcriptional unit
Uitto et al., Am J Pathol 1998
(Gingivitis...) :
In these cells,
MMP-13 expression at the mRNA and protein level was potently
enhanced ( up to sixfold ) by tumor necrosis factor-alpha, transforming growth factor-beta(1), and transforming growth factor-alpha and by
keratinocyte growth factor in the presence of heparin