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CDKN1A — RUNX1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Innatedb Interaction: RUNX1 — CDKN1A (unknown, -) Bakshi et al., J Cell Physiol 2010*
• IRef Innatedb Interaction: Complex of RUNX1-CDKN1A-CDKN1A (unknown, -) Wu et al., J Biol Chem 2013*

Text-mined interactions from Literome

Peterson et al., Blood 2007 (Leukemia...) : Thus, loss of p21 ( WAF1 ) facilitates AML1-ETO induced leukemogenesis, suggesting that mutagenic events in the p21 ( WAF1 ) pathway to bypass the growth inhibitory effect from AML1-ETO induced p21 ( WAF1 ) expression can be a significant factor in AML1-ETO associated acute myeloid leukemia
Hasegawa et al., Cancer Sci 2007 (Biliary Tract Neoplasms) : Based on these results, RUNX3 is involved in TGF-beta induced expression of p21 and the resulting induction of TGF-beta dependent G ( 1 ) arrest
Lee et al., Proc Natl Acad Sci U S A 2013 : Conversely, we find that Runx1 ( runt related transcription factor 1 ), which is known for promoting HFSC proliferation, represses p21 , p27, p57, and p15 transcription in HFSC in vivo