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CTLA4 — PI3

Text-mined interactions from Literome

Schneider et al., PloS one 2008 : CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B ( PKB/AKT ) sustains T-cell anergy without cell death ... In this study, we show that CTLA-4 activation of the phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B ( PKB/AKT ) sustains T-cell anergy without cell death
Reif et al., Curr Biol 1997 : Phosphoinositide 3-kinase ( PI 3-kinase ) is activated by a diverse set of receptors that determine T-cell function, including the T-cell antigen receptor ( TCR ), the costimulatory receptor CD28, and negative regulators of T-cell activation such as CTLA-4