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SULF2 — TCF7
Text-mined interactions from Literome
Lai et al., Hepatology 2010
(Carcinoma, Hepatocellular...) :
In HCC cells,
SULF2 increased cell surface GPC3 and Wnt3a expression, stabilized ß-catenin, and activated T cell factor
transcription factor activity and expression of the Wnt/ß-catenin target gene cyclin D1
Nakamura et al., J Biol Chem 2013
(Wnt Signaling Pathway) :
In isolated hepatocytes,
SULF2 deficiency
blocked WNT induced ß-CATENIN nuclear translocation,
TCF activation, and proliferation ... In isolated hepatocytes,
SULF2 deficiency
blocked WNT induced ß-CATENIN nuclear translocation,
TCF activation, and proliferation