Gene interactions and pathways from curated databases and text-mining

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KRT10 — NOS2

Text-mined interactions from Literome

Helmer et al., J Surg Res 2003 (Endotoxemia) : Because ketamine attenuates expression of several proinflammatory genes, we examined the effects of K/X on inducible nitric oxide synthase (iNOS) , which has been implicated in endotoxin induced tissue injury ... We hypothesized that K/X would attenuate LPS induced expression of iNOS in various organs in the rat ... K/X significantly attenuated LPS induced iNOS protein immunoreactivity in all of the aforementioned organs ( P < /= 0.05, all groups ) ... These data indicate that K/X attenuates LPS induced upregulation of iNOS in a variety of tissues
Jung et al., Otol Neurotol 2004 (Bone Resorption...) : NOS II was highly upregulated in response to keratin throughout the duration of the study