◀ Back to IFI27

IFI27 — PI3

Text-mined interactions from Literome

Murillo et al., Endocrinology 2001 (Disease Progression...) : At this stage, PI3K inhibition rapidly triggered accumulation of p27 ( kip1 ), cell cycle arrest, and cell death
Lee et al., Invest Ophthalmol Vis Sci 2003 : Regulatory role of PI 3-kinase on expression of Cdk4 and p27 , nuclear localization of Cdk4, and phosphorylation of p27 in corneal endothelial cells
Mirza et al., Mol Cell Biol 2004 (Pancreatic Neoplasms) : Consistent with these observations, pharmacological inhibition of MEK or PI3'-kinase inhibited the effects of activated RAS on the expression of p27 ( Kip1 ) in NIH 3T3 fibroblasts and in a panel of bona fide human pancreatic cancer cell lines
Fälker et al., Thromb Haemost 2005 : Finally, we demonstrate that tyrosine phosphorylation of p27 and p31 downstream of P2Y12 receptors is due to the inhibition of adenylyl cyclase but not phosphoinositide 3-kinase (PI 3-K) activation
Wu et al., Am J Respir Cell Mol Biol 2006 : CTGF induced HLF proliferation ; enhanced the expression of cyclin D1 ; phosphorylated extracellular signal regulated kinase ( ERK ) 1/2, phosphoinositide 3-kinase (PI3-K) , protein kinase B (PKB), and DNA binding activity of signal transducers and activators of transcription-3 ( STAT3 ) ; and inhibited expression of p27 ( kip1 )
Santra et al., J Cereb Blood Flow Metab 2006 (Glioma) : Blocking of phosphoinositide 3-kinase (PI-3K) , Ras, and the epidermal growth factor receptor with specific inhibitors had no effect on induction of Ras, p21, and p27 at the messenger RNA level in decorin synthesizing SVZ and U-87 cells
Charette et al., Oncogene 2007 : Using DNA damage as a p27 nuclear import signal, we found that the E7 oncoprotein from human papillomavirus type 16 ( HPV-16 ), the etiological agent of cervical cancer, enhanced both the cytoplasmic retention of p27 and the migration of human foreskin keratinocytes ( HFKs ) in a phosphoinositide-3 kinase (PI3K)/Akt dependent manner using a standard wound assay
Fukushima et al., Endocrinology 2008 : In contrast, IGF-I dependent PI 3-kinase activation was required for the increase in cyclin D1 mRNA levels and degradation of p27 ( Kip1 )
Zhang et al., Life Sci 2013 (Asthma...) : In the present study, we determined whether Phosphoinositide 3-kinase (PI3K) and Notch signal pathways are involved in the expression of cyclinD1, cyclinA and p27kip1 which were key molecules in controlling cell cycling from CD4 ( + ) T lymphocyte in animal model of asthma