◀ Back to AKT1
AKT1 — LOX
Text-mined interactions from Literome
Min et al., Cancer Res 2007
(Mammary Neoplasms, Experimental) :
LOX-PP expression in Her-2/neu-driven breast cancer cells in culture
suppressed Akt , extracellular signal regulated kinase, and nuclear factor-kappaB activation
Wu et al., Cancer Res 2007
(Lung Neoplasms...) :
Similarly,
LOX-PP expression in PANC-1 pancreatic cancer cells effectively
reduced ERK and
Akt activity and inhibited growth in soft agar and ability of these cells to migrate
Min et al., J Cell Biochem 2010
(Breast Neoplasms...) :
In MIA PaCa-2 cells in culture,
LOX-PP attenuated the ERK and
AKT activities and decreased the levels of the NF-?B p65 and RelB subunits and cyclin D1, which are activated by RAS signaling
Voloshenyuk et al., Cytokine 2011
(MAP Kinase Signaling System) :
Induction of cardiac fibroblast
lysyl oxidase by TGF-ß1
requires PI3K/Akt , Smad3, and MAPK signaling
Ji et al., Int J Oncol 2013
(Neoplasm Invasiveness...) :
Moreover, EOC cells display a marked increase in
LOX dependent
FAK/AKT activation and cell migration following hypoxia/reoxygenation