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ANGPT2 — HBEGF

Text-mined interactions from Literome

Uchiyama-Tanaka et al., Kidney Int 2001 : Ang II-mediated FN expression was regulated by autocrine effects of HB-EGF and TGF-beta, suggesting a novel paradigm for cross-talk between Ang II and growth factor receptor signaling pathways
Yang et al., Mol Cells 2005 (MAP Kinase Signaling System) : Furthermore Ang II-stimulated proliferation and migration of smooth muscle cells were significantly blunted by inhibiting MMPs and EGFR and applying HB-EGF neutralization antibody, indicating that MMPs, HB-EGF and EGFR activation is necessary for Ang-II stimulated migration and proliferation of smooth muscle cells