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EPHB2 — IL13

Text-mined interactions from Literome

Valledor et al., J Biol Chem 2000 : Granulocyte/macrophage colony stimulating factor, interleukin 3, and TPA, all of which induced macrophage proliferation, also induced ERK activity, which was maximal at 5 min poststimulation
Hirst et al., Am J Respir Crit Care Med 2002 : Activation of IL-4Ralpha by IL-13 or IL-4 induced signal transducer and activation of transcription-6 ( STAT6 ), p42/ p44 ERK , p38, and to a lesser extent, SAPK/JNK mitogen activated protein kinase phosphorylation
Maggi et al., J Biol Chem 2003 (Cardiovirus Infections...) : ERK activation is required for double stranded RNA- and virus induced interleukin-1 expression by macrophages
MacGillivray et al., J Biol Chem 2003 (MAP Kinase Signaling System) : The protein tyrosine phosphatase SHP-2 regulates interleukin-1 induced ERK activation in fibroblasts
Chang et al., J Biol Chem 2004 (Inflammation...) : The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation
Wang et al., J Biol Chem 2005 : SHP-2 modulates interleukin-1 induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1
Miranda et al., Leuk Res 2005 (MAP Kinase Signaling System) : Additionally, interleukin-3 , which inhibits G-CSF induced differentiation of 32 Dc l3 cells, also inhibited the ability of G-CSF to stimulate prolonged MEK/ERK activation
Lee et al., J Clin Invest 2006 (Inflammation) : We found that Tg IL-13 expression in the lung led to potent activation of ERK1/2 but not JNK1/2 or p38 ... Thus, ERK1/2 is activated by IL-13 in the lung in a STAT6 independent manner where it contributes to IL-13 induced inflammation and remodeling and is required for optimal IL-13 stimulation of specific chemokines and proteases as well as the inhibition of specific antiproteases
Zhou et al., J Allergy Clin Immunol 2007 (Asthma...) : ERK phosphorylation was increased by IL-13 and IL-13+TGF-beta1 ... These increases occur as TGF-beta1 downregulates IL-13 induced phosphoinositide-3 kinase activation while leaving the positive effect of IL-13 induced ERK on Smad signaling
Venkatachalam et al., Am J Physiol Heart Circ Physiol 2008 (Hyperglycemia) : Resveratrol inhibits high glucose induced PI3K/Akt/ERK dependent interleukin-17 expression in primary mouse cardiac fibroblasts
Fujisawa et al., Respirology 2008 (Metaplasia) : In contrast, ERK1/2 was constantly activated and was not enhanced by IL-13
Wu et al., Arch Biochem Biophys 2009 (MAP Kinase Signaling System) : The EGCG induced mRNA up-regulation of IL-2 and IL-5 was predominantly affected by the extracellular signal regulated protein kinase ( ERK ) signalling, whereas IL-13 gene expression, the most responsive to the EGCG treatment, was dependent on neither ERK nor c-jun NH ( 2 ) -terminal kinase ( JNK ) signalling
Woolson et al., Cell Signal 2009 : Here we demonstrate that elevation of cyclic AMP ( cAMP ) levels in human umbilical vein endothelial cells ( HUVECs ) specifically attenuates ERK1,2 activation in response to either leptin or a soluble interleukin IL-6 receptor-alpha/IL-6 ( sIL-6R alpha/IL-6 ) trans signalling complex but not protein kinase C activator phorbol 12-myristate 13-acetate
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Cuong et al., Life Sci 2009 (Inflammation...) : Pre-treatment with C-K significantly inhibited zymosan mediated secretion of tumor necrosis factor-alpha, interleukin (IL)-6 , and IL-12 p40, and the activation of ERK1/2 and p38
Kono et al., Pulm Pharmacol Ther 2010 (Asthma) : Furthermore, DMS inhibited IL-13 induced ERK1/2 phosphorylation but neither p38 MAPK nor STAT6 phosphorylation
Fujisawa et al., Int J Cancer 2012 (Neoplasm Invasiveness...) : Mechanistically, IL-13 enhanced ERK1/2 , AP-1 and MMP activities only in IL-13Ra2 positive cells but not in IL-13Ra2 negative cells
Lo et al., J Biol Chem 1998 : Requirements of focal adhesions and calcium fluxes for interleukin-1 induced ERK kinase activation and c-fos expression in fibroblasts