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AKT3 — PLK1

Text-mined interactions from Literome

Leonard et al., Cell cycle (Georgetown, Tex.) 2013 : In primary keratinocytes, knockdown of PTEN increased whole-cell levels of ?-tubulin and PLK-1 in an Akt dependent manner and had little effect on recruitment of either protein to mitotic centrosomes ... Inhibition of Akt activation with MK2206 reduced the whole-cell and centrosome levels of PLK-1 and ?-tubulin and also prevented the recruitment of PTEN to mitotic centrosomes ... Inhibition of Akt activation with MK2206 reduced the whole-cell and centrosome levels of PLK-1 and ?-tubulin and also prevented the recruitment of PTEN to mitotic centrosomes
Kasahara et al., Nature communications 2013 : Inhibition of phosphatidylinositol 3-kinase (PI3K) and Akt significantly reduces the level of Plk1-Ser99 phosphorylation and delays metaphase to anaphase transition ... Plk1-Ser99 phosphorylation requires not only Akt activity but also protein ( s ) associated with Plk1 in a mitosis-specific manner