◀ Back to APOB
APOB — GH1
Text-mined interactions from Literome
Lind et al., Arterioscler Thromb Vasc Biol 2004
(Hyperlipoproteinemia Type II...) :
Growth hormone (GH) induces hepatic
low-density lipoprotein (LDL) receptors and lowers plasma cholesterol
Hansen et al., Metabolism 1995
:
The
effect of recombinant human
growth hormone ( rHGH ) on cholesterol, high- and low-density lipoprotein ( HDL and LDL ) cholesterol, triglycerides ( TG ),
apolipoprotein ( apo ) B , apo A-I, and lipoprotein ( a ) [ Lp(a)] was studied in 40 postmenopausal women treated with 0.05, 0.1, or 0.2 IU/kg/d rHGH or placebo for 7 days
Tonstad et al., Metabolism 1996
(Hyperlipoproteinemia Type II) :
We conclude that the effect of
growth hormone on LDL cholesterol levels in FH is less than expected, based on its LDL-catabolic effects, and is counteracted by profound increases in Lp(a) levels,
resulting in unchanged levels of
apolipoprotein B
Parini et al., Arterioscler Thromb Vasc Biol 1997
:
The known role of
growth hormone for the expression of hepatic ERs may therefore
play a role in the modulation of the effects of estrogen on cholesterol metabolism and hepatic
LDL receptors in the rat