Gene interactions and pathways from curated databases and text-mining

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APOB — GH1

Text-mined interactions from Literome

Lind et al., Arterioscler Thromb Vasc Biol 2004 (Hyperlipoproteinemia Type II...) : Growth hormone (GH) induces hepatic low-density lipoprotein (LDL) receptors and lowers plasma cholesterol
Hansen et al., Metabolism 1995 : The effect of recombinant human growth hormone ( rHGH ) on cholesterol, high- and low-density lipoprotein ( HDL and LDL ) cholesterol, triglycerides ( TG ), apolipoprotein ( apo ) B , apo A-I, and lipoprotein ( a ) [ Lp(a)] was studied in 40 postmenopausal women treated with 0.05, 0.1, or 0.2 IU/kg/d rHGH or placebo for 7 days
Tonstad et al., Metabolism 1996 (Hyperlipoproteinemia Type II) : We conclude that the effect of growth hormone on LDL cholesterol levels in FH is less than expected, based on its LDL-catabolic effects, and is counteracted by profound increases in Lp(a) levels, resulting in unchanged levels of apolipoprotein B
Parini et al., Arterioscler Thromb Vasc Biol 1997 : The known role of growth hormone for the expression of hepatic ERs may therefore play a role in the modulation of the effects of estrogen on cholesterol metabolism and hepatic LDL receptors in the rat