Saxena et al., J Biol Chem 2007
(Breast Neoplasms...) :
We also show specific involvement of coactivator molecules, histone acetyltransferase SRC1, and mediator complex in leptin mediated regulation of CYCLIN D1 promoter
Sirotkin et al., Physiol Res 2008
:
It was observed that leptin stimulated in a dose dependent manner the accumulation of PCNA ( at doses 1-100 ng/ml ), cyclin B1 ( at doses 10 or 100 ng/ml ), Bax ( at doses 10 or 100 ng/ml ) and PKA ( at doses 1-100 ng/ml ) in cultured human ovarian cells
Sirotkin et al., Comp Biochem Physiol A Mol Integr Physiol 2007
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Furthermore, leptin inhibited expression of PCNA ( marker of S-phase of mitosis ), but not of cyclin B1 ( marker of G phase of cell cycle )