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IL6 — STS

Text-mined interactions from Literome

Vanden Berghe et al., J Biol Chem 1999 : Expression of the pleiotropic cytokine interleukin (IL)-6 can be stimulated by the proinflammatory cytokine tumor necrosis factor (TNF) and the microbial alkaloid staurosporine (STS) ... Moreover, treatment of chromatin integrated promoter constructions with the histone deacetylase inhibitor trichostatin A exclusively potentiates TNF dependent ( i.e. NF-kappaB mediated ) gene activation, while basal or STS stimulated IL-6 promoter activity remains completely unchanged
Newman et al., J Steroid Biochem Mol Biol 2000 (Breast Neoplasms) : TNFalpha plus IL-6 increased STS activity in mock transfected MCF-7 cells and further increased STS activity in transfected MCF-7 cells ... In conjunction with the lack of regulation of STS mRNA it suggest that TNFalpha and IL-6 may increase STS activity via a post-translational modification of the enzyme or by increasing substrate availability
Honma et al., Endocr J 2002 (Breast Neoplasms) : IL-6 and IL-1 beta stimulated the activity of Arom and STS
Ren et al., Mol Med Report 2013 : Data showed that ASC overexpression induced by pEGFP-ASC-C2 transfection significantly increased caspase-1 expression and interleukin (IL)-1ß and IL-6 secretion, but did not affect tumor necrosis factor (TNF)-a secretion
Im et al., Biomolecules & therapeutics 2012 : We investigated that LPS induced IL-6 expression and IL-6 increased STS expression