Gene interactions and pathways from curated databases and text-mining

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HCFC1 — IL6

Text-mined interactions from Literome

Maertzdorf et al., J Immunol 2002 (Keratitis, Herpetic) : IL-17 exhibited a strong synergistic effect with TNF-alpha on the induction of IL-6 and IL-8 secretion by cultured HCF
Ohyama et al., Biol Pharm Bull 2004 (Influenza, Human) : In IV-infected HCF , gene mRNA expression levels of interleukine (IL)-1beta, IL-6 , tumor necrosis factor (TNF) alpha, Fas ligand, interferon regulatory factor (IRF)-1, interferon ( IFN ) alpha and IFN beta increased as compared with those in mock treatment cells, and the induction of mRNAs for double stranded RNA dependent protein kinase ( PKR ), indolamine 2,3-deoxygenase (IDO) and 2'-5 ' oligoadenylate synthetase ( 2-5 OAS ) were indicated, which had a role for a host defense response induced by IFN-beta