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CXCL1 — IL8

Pathways - manually collected, often from reviews:

• Reactome Reaction: CXCL1 → IL8 (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Ribaux et al., Endocrinology 2007 : Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells
Lai et al., Int J Gynecol Cancer 2011 (Genital Neoplasms, Female...) : Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1, CXCL2, IL-6, and IL-8 increased ... Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2, IL-6, and IL-8 , and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1 , CXCL2, IL-6, and IL-8 increased
Lee et al., Eur Respir J 2012 (Inflammation...) : NRF knockdown enhanced IL-8/CXCL8 production in normal PBMCs, whilst NRF overexpression attenuated IL-8/CXCL8 production
Gayle et al., J Biol Chem 1993 : The ability of the chimeric receptors to bind IL-8 was determined, as well as the ability of IL-8 and GRO/MGSA to inhibit radiolabeled IL-8 binding
Sanchez et al., J Immunol 1998 : Finally, the IC50 of IL-8- and MGSA dependent suppression of proliferation of 32D cells is in good agreement with the EC50 of IL-8- and MGSA dependent activation of neutrophil Mac-1 up-regulation and chemotaxis