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CTNNB1 — PXN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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MIPS CORUM Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1):
Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1) complex (ACTN1-BCAR1-CDH1-CTNNB1-JUP-PKD1-PTK2-PXN-SRC-TLN1-VCL)
Geng et al., Biochim Biophys Acta 2000
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IRef Corum Interaction:
Complex of 12 proteins
(association, cosedimentation through density gradient)
Geng et al., Biochim Biophys Acta 2000
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IRef Intact Interaction:
PXN
—
CTNNB1
(physical association, anti bait coimmunoprecipitation)
Dubrovskyi et al., FEBS Lett 2012*
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IRef Intact Interaction:
PXN
—
CTNNB1
(direct interaction, pull down)
Dubrovskyi et al., FEBS Lett 2012*
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IRef Intact Interaction:
PXN
—
CTNNB1
(physical association, pull down)
Dubrovskyi et al., FEBS Lett 2012*
Text-mined interactions from Literome
Birukova et al., Am J Physiol Lung Cell Mol Physiol 2007
:
Depletion of
beta-catenin using the siRNA approach
attenuated OxPAPC induced
paxillin translocation to the cell periphery, but also significantly decreased interaction of paxillin with AJ protein complex
Chatterjee et al., Am J Physiol Lung Cell Mol Physiol 2008
(Sepsis) :
Pretreatment with the hsp90 inhibitor, radicicol, prevented the decrease in TER, maintained VE-cadherin and
beta-catenin expression, and
inhibited activation of pp60 ( Src ) and phosphorylation of
paxillin