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APOE — IL6
Text-mined interactions from Literome
Patel et al., Neurosci Lett 2004
:
In adult glia,
IL-6 increased
ApoE secretion, but slightly decreased ApoJ ... In contrast to adult glia, neonatal ApoJ secretion did not respond to IL-1 beta, IL-6, or TNFalpha, and
ApoE secretion from neonatal glia was slightly
increased by
IL-6
Yamagata et al., Neurochem Int 2013
(Stroke) :
Dietary ß-carotene regulates
interleukin-1ß induced expression of
apolipoprotein E in astrocytes isolated from stroke-prone spontaneously hypertensive rats
Wei et al., Neurobiol Dis 2013
:
We observed that the absence of
apoE resulted in the increased proportion of Th1 and Th17 cells in the spleens and brains, as well as up-regulated expressions of proinflammatory cytokines ( IL-17, IFN-?, TNF-a, IL-12, IL-1ß and
IL-6 ) and transcription factors ( ROR?t and T-bet ) in the CNS
Fuhrman et al., Atherosclerosis 1994
:
Macrophage lipid peroxidation increases cell mediated oxidation of LDL, enhances the release of
interleukin 1 and
inhibits the release of
apolipoprotein E from the macrophages