Gene interactions and pathways from curated databases and text-mining

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ICOS — IL13

Text-mined interactions from Literome

Riley et al., J Immunol 2001 : Second, on preactivated cells that had high levels of ICOS expression, CTLA-4 ligation blocked the ICOS mediated induction of IL-4, IL-10, and IL-13 , suggesting an interference with downstream signaling pathways
Wahl et al., J Am Soc Nephrol 2002 : Interestingly, interleukin-2 production by T cell hybridomas after antigen presentation by TEC was enhanced by blocking antibodies to B7RP-1 and ICOS
Zietara et al., Eur J Immunol 2011 : NKT-cell proliferation, IL-4 and IL-13 production induced by MZ B cells were dependent on ICOS/ICOS ligand interaction while IFN-? and IL-17 induction by cDCs required glucocorticoid induced TNF receptor/glucocorticoid induced TNF receptor ligand interplay