Gene interactions and pathways from curated databases and text-mining

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EGR1 — IL2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Liu et al., Cell Growth Differ 1993 (Carcinoma, Hepatocellular...) : Other similar cytokines were investigated, and, of these, only interleukin 1 could increase both Egr-1 and LDL receptor activity
Lin et al., Mol Cell Biol 1997 : Thus, Sp1 and Egr-1 physically and functionally cooperate to mediate maximal IL-2Rbeta promoter activity
Azzoni et al., J Immunol 1998 : We previously demonstrated that expression of transcription factors ( e.g., Egr-1 , JunB, and c-Fos ) is differentially regulated by IL-2 and IL-12