Gene interactions and pathways from curated databases and text-mining

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IL6 — NMU

Text-mined interactions from Literome

Moriyama et al., Biochem Biophys Res Commun 2006 (Shock, Septic) : The neuropeptide neuromedin U promotes IL-6 production from macrophages and endotoxin shock ... In this study, we demonstrated that NMU plays an important role in IL-6 production in macrophages ... These data suggest that LPS induced IL-6 expression is partly dependent on autocrine/paracrine activation of the NMU-NMU-R1 signals in macrophages
Iwai et al., Neurosci Res 2008 (Inflammation...) : Real-time PCR based experiments indicated that NmU did not affect the mRNA level of IL-1beta or IL-6 increased by LPS, whereas it increased that of brain derived neurotrophic factor (BDNF) in the hippocampus