Santini et al., Haematologica 2002
:
The phosphorylation of Syk kinase was not demonstrated, whereas Vav was activated by TPO Dorsch et al., J Exp Med 1997
:
This mutant still mediates TPO induced phosphorylation of Shc, Vav , mitogen activated protein kinase ( MAPK ) and Raf-1 as well as induction of c-fos and c-myc, although at somewhat reduced levels