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EPHB2 — FLT4

Text-mined interactions from Literome

Taniguchi et al., Mol Cell Biol 2007 : In cultured cells, the overexpression of Spred-1 or Spred-2 strongly suppressed vascular endothelial growth factor-C ( VEGF-C ) /VEGF receptor (VEGFR)-3 mediated ERK activation, while Spred-1/2-deficient cells were extremely sensitive to VEGFR-3 signaling
Luo et al., Oncogene 2011 : Overexpression of VEGFR-3 attenuated CPX inhibition of ERK1/2 phosphorylation, whereas downregulation of VEGFR-3 inhibited ERK1/2 phosphorylation in LECs
Luo et al., Cancer prevention research (Philadelphia, Pa.) 2011 : Overexpression of VEGFR-3 attenuated CPT inhibition of ERK1/2 phosphorylation, whereas downregulation of VEGFR-3 inhibited ERK1/2 phosphorylation in LECs ... Taken together, the results suggest that CPT inhibits LEC tube formation, in part, by inhibiting VEGFR-3 mediated ERK1/2 phosphorylation and, in part, by inhibiting expression of the small GTPases