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OSM — RELA
Text-mined interactions from Literome
Nishibe et al., Blood 2001
(MAP Kinase Signaling System) :
Activation of
NF-kappaB by
OSM did not require IkappaB-alpha degradation
Baker et al., Glia 2010
:
OSM regulates gene expression primarily by activating the JAK/STAT,
NF-kappaB , and/or MAPK pathways, in a cell-type specific manner ... In our studies,
OSM induces the production of the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS) from microglia in an
NF-kappaB dependent manner