◀ Back to PTPN1
CTNNB1 — PTPN1
Pathways - manually collected, often from reviews:
-
KEGG Adherens junction:
PTPN1
→
CTNNB1
(protein-protein, activation)
-
NCI Pathway Database Posttranslational regulation of adherens junction stability and dissassembly:
PTP1B (PTPN1)
→
beta catenin/alpha catenin complex (CTNNB1-CTNNA1)
(modification, activates)
Xu et al., J Biol Chem 2002, Xu et al., J Cell Sci 2004, Tai et al., Neuron 2007, Balsamo et al., J Cell Biol 1998
Evidence: assay, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lilien et al., Dev Dyn 2002
:
Our laboratory has focused on the
role of the nonreceptor tyrosine phosphatase
PTP1B in regulating the phosphorylation of
beta-catenin on tyrosine residues
Xu et al., J Cell Sci 2004
:
We now show that the phosphorylation of
beta-catenin is
regulated by the combined activities of the tyrosine kinase Fer and the tyrosine phosphatase
PTP1B