Gene interactions and pathways from curated databases and text-mining

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CARF — MDM2

Text-mined interactions from Literome

Kaul et al., Ann N Y Acad Sci 2006 : We demonstrate that p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2
Cheung et al., Mech Ageing Dev 2009 : Whereas CARF transcriptionally represses HDM2 to increase p53 activity, HDM2 in return degrades CARF