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CD3D — SYK

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• Gene Ontology Complexes T cell receptor complex: T cell receptor complex complex (CD247-SYK-CD8B-CD3D-ZAP70) Allam et al., Immunobiology 2000*, Weissman et al., Nature 1986*, Chan et al., J Immunol 1994, San José et al., Eur J Immunol 1998
• STRING interaction: CD3D — SYK (interaction, mapped from reactome)
• STRING interaction: SYK — CD3D (interaction, mapped from reactome)

Text-mined interactions from Literome

Krishnan et al., J Immunol 2003 : The TCR/CD3/FcRgamma complex in effector cells recruits and activates the Syk , but not the ZAP-70, tyrosine kinase
Umehara et al., Int Immunol 1998 : Co-stimulation of T cells with CD2 augments TCR-CD3 mediated activation of protein tyrosine kinase p72syk , resulting in increased tyrosine phosphorylation of adapter proteins, Shc and Cbl