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CD14 — IL33
Text-mined interactions from Literome
Iwagaki et al., Infect Immun 2000
:
The purpose of this study was to compare and contrast the endotoxin neutralizing activities of two synthetic antiendotoxin peptides ( SAEP-2 and SAEP-4 ), PMB, and an LPS core-specific monoclonal antibody ( MAb ), WN1 222-5, based on their abilities to inhibit
CD14 mediated target cell uptake of fluorescein isothiocyanate ( FITC ) -conjugated LPS, detected by flow cytometry and confocal microscopy, and LPS induced production of the proinflammatory cytokines,
interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha), as measured by bioassays
Espinassous et al., J Immunol 2009
(Inflammation) :
Our results show that
IL-33 increases the expression of the LPS receptor components MD2 ( myeloid differentiation protein 2 ) and TLR-4, the soluble form of
CD14 and the MyD88 adaptor molecule