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IL1A — MAP3K1

Pathways - manually collected, often from reviews:

• BioCarta nf-kb signaling pathway: IL-1/IL-1R/MYD88/IRAK/TRAF6 complex (IL1A-IL1R1-MYD88-IRAK1-TRAF6) → IKK-alpha/MEKK1/NIK complex (CHUK-MAP3K1-MAP4K4) (modification, activates)
  

Text-mined interactions from Literome

Yujiri et al., Proc Natl Acad Sci U S A 2000 : MEKK1 is not required for TNFalpha or IL-1 regulation of JNK or NF-kappaB activation in macrophages or fibroblasts
Al-Sadi et al., Am J Pathol 2010 : Our results showed that IL-1ß caused a rapid activation of MEKK-1 and NIK