Gene interactions and pathways from curated databases and text-mining

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CDC37 — CDK7

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Jallepalli et al., Genes Dev 1996 : Rum1 and Cdc18 link inhibition of cyclin dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
Kimura et al., Genes Dev 1997 : Cdc37 is required for cyclin dependent kinase activation and is genetically linked with the activity of several other kinases, including oncogenic v-Src, casein kinase II, MPS-1 kinase, and sevenless
Sutton et al., Genetics 1997 : Analysis of several different cak1 mutants shows that although the G2 to M transition appears most sensitive to loss of Cak1p function, Cak1p is also required for activation of Cdc28p for progression from G1 into S phase
Espinoza et al., Mol Cell Biol 1998 : Cak1 is required for the phosphorylation and activation of Cdc28 , a major CDK involved in cell cycle control