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IL5 — SPP1
Text-mined interactions from Literome
Koguchi et al., Infect Immun 2002
(AIDS-Related Opportunistic Infections) :
Penicillium marneffei causes
osteopontin mediated production of
interleukin-12 by peripheral blood mononuclear cells
Himeno et al., J Bone Miner Res 2002
(Ossification, Heterotopic) :
In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1, platelet derived growth factor ( PDGF ),
interleukin (IL)-1beta , and thyroid hormone ( T3 )
induced osteopontin and MMP-13 expression
Mas et al., Mult Scler 2007
(Genetic Predisposition to Disease...) :
OPN enhances the production of the pro-inflammatory cytokines,
interleukin-12 and interferon-gamma, while reducing interleukin-10 levels
Lu et al., Allergy 2009
(Nasal Polyps...) :
On the contrary,
OPN induced IFN-gamma, IL-4,
IL-5 , IL-13, IL-1beta, and TNF-alpha production in sinonasal mucosa
Diao et al., Cytokine 2012
(Drug-Induced Liver Injury...) :
Osteopontin regulates
interleukin-17 production in hepatitis
Singh et al., J Biol Chem 1995
:
In vitro,
interleukin-1 beta and interferon-gamma
increased osteopontin mRNA levels in CMEC as well as NOS2 expression in both CMEC and cardiac myocytes