Gene interactions and pathways from curated databases and text-mining

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BDNF — GAP43

Text-mined interactions from Literome

Encinas et al., J Neurochem 1999 (Neuroblastoma) : The mitogen activated protein kinase and ERK kinase ( MEK ) inhibitor PD98059 blocks BDNF induced neurite outgrowth and growth associated protein-43 expression but has no effects on cell survival
Young et al., J Neurosci Methods 1999 : The effects of nerve growth factor (NGF), neurotrophin-3 (NT-3) and brain derived neurotrophic factor (BDNF) on GAP-43 immunoreactivity in dissociated primary cultures of rat and chick dorsal root ganglia have been compared to results obtained by cell counting
Klöcker et al., Neurobiol Dis 2001 : Here, we characterized the effects of the survival promoting neurotrophin brain derived neurotrophic factor (BDNF) on mRNA expression of GAP-43 , L1, TAG-1, and SC-1 in axotomized and regenerating rat retinal ganglion cells ( RGCs ) ... This led us to hypothesize that the BDNF effects on GAP-43 , L1, and TAG-1 mRNA expression are mediated by a NO-dependent mechanism
Leaver et al., Gene Ther 2006 (Optic Nerve Injuries) : At 7 weeks after ON crush, quantification of betaIII-tubulin immunostaining revealed that, compared to AAV-GFP controls, RGC survival was not enhanced by AAV-GAP43-GFP but was increased in AAV-CNTF-GFP ( mean RGCs/retina : 17 450+/-358 s.e.m. ) and AAV-BDNF-GFP injected eyes ( 10 200+/-4064 RGCs/retina )
Wang et al., Nan Fang Yi Ke Da Xue Xue Bao 2010 : [ Effect of endogenous brain derived neurotrophic factor on GAP-43 expression in the anterior horn of the spinal cord in rats with sciatic nerve injury ] ... To investigate the effect of endogenous brain derived neurotrophic factor (BDNF) on GAP-43 expression in the anterior horn of the spinal cord in rats following sciatic nerve injury ... Endogenous BDNF may regulate the expression of GAP-43 in the spinal cord anterior horn after sciatic nerve injury in rats
Fournier et al., J Neurosci Res 1997 (Optic Nerve Injuries) : We conclude that BDNF specifically enhances GAP-43 but not T alpha1 mRNA levels in injured RGCs