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ERBB2 — YY1

Text-mined interactions from Literome

Begon et al., J Biol Chem 2005 (Breast Neoplasms) : In this report, we examined the cooperative effect of Yin Yang 1 (YY1) on AP-2 induced activation of ERBB2 promoter activity ... Notably, we showed that YY1 enhances AP-2alpha transcriptional activation of the ERBB2 promoter through an AP-2 site both in HepG2 and in HCT116 cells, whereas a carboxyl-terminal truncated form of YY1 can not
Allouche et al., Breast Cancer Res 2008 (Breast Neoplasms) : The functional role of AP-2alpha and YY1 on ERBB2 gene expression was analyzed by small interfering RNA ( siRNA ) transfection in the BT-474 mammary cancer cell line followed by real-time reverse transcription-polymerase chain reaction and Western blotting ... This study highlights the role of both AP-2alpha and YY1 transcription factors in ERBB2 oncogene overexpression in breast tumors