Gene interactions and pathways from curated databases and text-mining

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EPX — IL6

Text-mined interactions from Literome

Faquin et al., Blood 1992 (Inflammation) : However, IL-6 did not stimulate Epo synthesis in the absence of hypoxia, and was thus synergistic with hypoxia in inducing Epo production
Vannucchi et al., Br J Haematol 1994 : According to previous observations, IL-6 had a stimulatory effect on Epo production by CoCl2 treated Hep3B cells ; however, the simultaneous addition of IFN-gamma and IL-6 resulted in a reversal of the stimulatory effects due to IL-6
Jelkmann et al., Ann N Y Acad Sci 1994 (Anemia...) : IL-6 stimulated the production of EPO in Hep3B cells but was ineffective in HepG2 cells and lowered EPO production in isolated perfused rat kidneys