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BTRC — NFKB1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Canonical NF-kappaB pathway: beta TrCP1/SCF ubiquitin ligase complex complex (BTRC) → NF kappa B1 p50/RelA/I kappa B alpha complex (NFKB1-NFKBIA-RELA) (modification, activates)
  
• NCI Pathway Database Canonical NF-kappaB pathway: beta TrCP1/SCF ubiquitin ligase complex complex (BTRC) → NF kappa B1 p50/RelA complex (NFKB1-RELA) (modification, activates)
  
• NCI Pathway Database Atypical NF-kappaB pathway: NF kappa B1 p105 (NFKB1) → beta TrCP1/SCF ubiquitin ligase complex complex (BTRC) (modification, collaborate)
  
• NCI Pathway Database Atypical NF-kappaB pathway: beta TrCP1/SCF ubiquitin ligase complex complex (BTRC) → NF kappa B1 p105/p50 complex (NFKB1) (modification, activates)
  
• Reactome Reaction: BTRC → NFKB1 (indirect_complex) Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Lang et al., Mol Cell Biol 2003*, Cohen et al., Mol Cell Biol 2004, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999
• Reactome Reaction: BTRC → NFKB1 (reaction) Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Lang et al., Mol Cell Biol 2003*, Cohen et al., Mol Cell Biol 2004, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: Complex of 25 proteins Bouwmeester et al., Nat Cell Biol 2004
• IRef Biogrid Interaction: BTRC — NFKB1 (physical association, affinity chromatography technology) Busino et al., Nat Cell Biol 2012
• IRef Biogrid Interaction: BTRC — NFKB1 (direct interaction, enzymatic study) Amir et al., J Biol Chem 2002*
• IRef Biogrid Interaction: BTRC — NFKB1 (physical association, affinity chromatography technology) Heissmeyer et al., Mol Cell Biol 2001*
• IRef Biogrid Interaction: BTRC — NFKB1 (physical association, affinity chromatography technology) Lang et al., Mol Cell Biol 2003*
• IRef Biogrid Interaction: BTRC — NFKB1 (direct interaction, pull down) Lang et al., Mol Cell Biol 2003*
• IRef Biogrid Interaction: BTRC — NFKB1 (direct interaction, pull down) Winston et al., Genes Dev 1999
• IRef Biogrid Interaction: BTRC — NFKB1 (physical association, affinity chromatography technology) Winston et al., Genes Dev 1999
• IRef Hprd Interaction: BTRC — NFKB1 (in vivo) Orian et al., EMBO J 2000*, Lang et al., Mol Cell Biol 2003*
• IRef Hprd Interaction: BTRC — NFKB1 (in vitro) Orian et al., EMBO J 2000*, Lang et al., Mol Cell Biol 2003*
• IRef Innatedb Interaction: BTRC — NFKB1 (unknown, -) Heissmeyer et al., Mol Cell Biol 2001*
• IRef Innatedb Interaction: BTRC — NFKB1 (unknown, -) Orian et al., EMBO J 2000*
• IRef Innatedb Interaction: BTRC — NFKB1 (unknown, -) Lang et al., Mol Cell Biol 2003*

Text-mined interactions from Literome

Spiegelman et al., J Biol Chem 2001 : Induction of beta-transducin repeat containing protein by JNK signaling and its role in the activation of NF-kappaB
Wang et al., Arterioscler Thromb Vasc Biol 2004 : The role of [ beta]-transducin repeat containing protein ( [ beta ] -TrCP ) in the regulation of NF-[kappa]B in vascular smooth muscle cells
Wong et al., Allergy 2006 : The induction of RANTES by SCF or TNF-alpha was mediated by ERK and NF-kappaB , respectively, and SCF induced MIP-1beta release was mediated by ERK