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GFAP — VIM
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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IRef Biogrid Interaction:
VIM
—
GFAP
(direct interaction, two hybrid)
Rual et al., Nature 2005
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Gene Ontology Complexes intermediate filament:
intermediate filament complex (KRT39-KRT38-KRTAP4-2-KRT31-NME1-NME2-KRT32-KRT35-KRT34-KRT37-KRT36-KRT222-KRTAP4-6-KRTAP3-1-MICAL1-KRTAP1-1-KRT28-KRTAP1-3-KRTAP1-4-KRTAP1-5-KRT23-KRT20-KRT26-KRT27-KRT24-KRT25-LMNTD1-KRTAP21-3-KRTAP27-1-KRTAP20-2-KRTAP20-3-KRTAP20-1-KRTAP20-4-KRTAP10-8-KRTAP6-2-KRTAP10-5-KRTAP10-4-KRTAP10-3-KRTAP10-2-KRTAP10-1-VIM-KRTAP23-1-KRTAP25-1-SYNM-DES-SYNC-PRPH-FLG-KRTAP4-9-KRTAP9-9-KRTAP7-1-KRTAP9-1-KRTAP9-2-KRTAP9-3-KRTAP9-4-KRTAP4-4-KRTAP9-6-KRTAP9-7-JUP-KRT40-KRTAP10-12-DSP-KRTAP10-10-KRTAP12-1-GJA1-KRTAP12-3-KRTAP12-2-KRTAP12-4-KRTAP24-1-KRT17-KRT16-KRT15-KRT14-KRT12-KRT10-INA-KRT19-KRT18-KRT75-KRT74-KRT77-KRT76-KRT71-KRT73-KRT72-KRT79-KRT78-KRT3-KRT2-KRT1-KRT7-KRT4-KRT9-KRT8-NES-KRTAP5-10-KRT80-KRT81-KRT82-KRT83-KRT84-KRT85-KRT86-KRTAP19-2-KRTAP19-3-KRTAP19-1-KRT6B-KRT6C-KRTAP19-4-KRT6A-KRTAP19-6-KRTAP19-8-KRTAP19-7-KRTAP5-4-LMNB2-KRTAP5-6-KRTAP5-7-KRTAP5-1-KRTAP5-2-KRTAP5-3-KRTAP2-3-KRTAP2-1-KRTAP19-5-KRTAP5-9-KRTAP15-1-LMNB1-KRTAP4-16P-KRTAP2-4-KRTAP16-1-KRTAP21-2-KRTAP21-1-KRTAP11-1-KRTAP22-1-KRTAP22-2-KRTAP5-5-EIF6-KRTAP4-5-KRTAP8-1-KRTAP29-1-NCKIPSD-KRT87P-NEFL-KRT33A-KRTAP6-3-NEFH-KRTAP6-1-CLIP1-KRTAP17-1-GFAP-KRTAP4-8-KRTAP3-2-BFSP2-MNS1-BFSP1-KRTAP13-4-KRTAP13-1-KRTAP13-2-KRTAP13-3-KRTAP4-11-LMNA-KRTAP4-12-KRTAP26-1-KRTAP3-3-NEFM-KRT33B-SLC1A4-KRTAP4-3)
de Bernard et al., EMBO J 2000, Hofmann et al., J Cell Sci 2000, Suzuki et al., J Biol Chem 2002, Collin et al., Differentiation 1992, Collin et al., Exp Cell Res 1992, Bilbe et al., EMBO J 1992, Yang et al., Circ Res 2006, Langbein et al., J Biol Chem 2010, Glass et al., J Cell Biol 1985, Leube et al., J Cell Biol 1988, Zhou et al., J Biol Chem 1988, McKinley-Grant et al., Proc Natl Acad Sci U S A 1989, Moll et al., Differentiation 1993, Ku et al., J Biol Chem 1997, Irvine et al., Nat Genet 1997, Winter et al., J Biol Chem 1997, Hess et al., Exp Eye Res 1998, Muñoz-Mármol et al., Proc Natl Acad Sci U S A 1998, Yaworsky et al., Dev Biol 1999
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IRef Hprd Interaction:
VIM
—
GFAP
(two hybrid)
Rual et al., Nature 2005
-
IRef Intact Interaction:
VIM
—
GFAP
(physical association, two hybrid pooling approach)
Rual et al., Nature 2005
-
IRef Ophid Interaction:
VIM
—
GFAP
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Acarin et al., Neuroscience 1999
:
Interestingly, thalamic reactive astrocytes showed increased
glial fibrillary acidic protein expression but no
induction of
vimentin and metallothionein I-II
Hernandez et al., Molecular vision 2009
(Glaucoma) :
Glial fibrillary acidic protein and
vimentin expression in glial cells
increased after one week of elevated IOP
Yoshii et al., Neurosci Res 2011
(Amyotrophic Lateral Sclerosis...) :
Further, at the end stage of disease, loss of
GFAP resulted in increased levels of
Vim and Aif1 mRNAs, encoding vimentin and allograft inflammatory factor 1 (AIF1), respectively, in the spinal cord, although no discernible differences in the levels and distribution of these proteins between SOD1 ( H46R ) and GFAP-deficient SOD1 ( H46R ) mice were observed