UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to EDNRB

EDNRB — PLCB1

Pathways - manually collected, often from reviews:

NCI Pathway Database Endothelins: None → ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) (modification, collaborate)
Aramori et al., J Biol Chem 1992, Takuwa et al., Am J Physiol 1989, Resink et al., Biochem Biophys Res Commun 1988
Evidence: assay, other species
NCI Pathway Database Endothelins: ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) (modification, activates) Aramori et al., J Biol Chem 1992, Takuwa et al., Am J Physiol 1989, Resink et al., Biochem Biophys Res Commun 1988
Evidence: assay, other species
NCI Pathway Database Endothelins: ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) → None (modification, activates) Aramori et al., J Biol Chem 1992, Takuwa et al., Am J Physiol 1989, Resink et al., Biochem Biophys Res Commun 1988
Evidence: assay, other species
NCI Pathway Database Endothelins: ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) → p38 alpha (MAPK14) (modification, activates) Aquilla et al., J Biol Chem 1996
Evidence: mutant phenotype, other species
NCI Pathway Database Endothelins: ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) → PLC beta (PLCB3/PLCB2/PLCB1) (modification, collaborate)
Aramori et al., J Biol Chem 1992
NCI Pathway Database Endothelins: ETB receptor/Endothelin-1/Gq/GTP/PLC beta complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14-PLCB3_PLCB2_PLCB1) → ETB receptor/Endothelin-1/Gq/GTP complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14) (modification, collaborate)
Aramori et al., J Biol Chem 1992
NCI Pathway Database Endothelins: PLC beta (PLCB3/PLCB2/PLCB1) → ETB receptor/Endothelin-1/Gq/GTP complex (EDNRB-EDN1-GNA11_GNAQ_GNA15_GNA14) (modification, collaborate)
Aramori et al., J Biol Chem 1992