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IL23A — TLR4

Text-mined interactions from Literome

Carmody et al., J Immunol 2007 : Essential roles of c-Rel in TLR induced IL-23 p19 gene expression in dendritic cells
Karrasch et al., J Immunol 2007 (Colitis...) : IL-10-/- ; MyD88-/- mice were used to assess E. faecalis/E. coli induced TLR dependent signaling and IL-23 gene expression
van Beelen et al., Immunity 2007 (Bacterial Infections...) : MDP enhanced obligate bacterial Toll-like receptor ( TLR ) agonist induction of IL-23 and IL-1, which promoted IL-17 expression in T cells
Siegemund et al., Immunobiology 2007 : Using BMDC originating from wild-type ( wt ), TLR2 ( def ) and TLR4 ( def ) mice, we show that in BMDC the induction of IL-12, IL-23 , and IL-27p28 by SE is dependent on TLR4 , whereas low-level production of p40 is also mediated by pattern recognition receptors ( PRR ) other than TLR4
Liu et al., J Immunol 2009 (Shock, Hemorrhagic) : We demonstrate that HS/R through the alarmin HMGB1 induces IL-23 secretion from macrophages in an autocrine and TLR4 signaling dependent manner
Hayashi et al., Immunology 2010 : In the present study, we examined the effect of prostaglandin E ( 2 ) ( PGE ( 2 ) ) treatment of DCs during differentiation on IL-12 and IL-23 production in response to Toll-like receptor ( TLR ) stimulation
Goodall et al., Proc Natl Acad Sci U S A 2010 (Chlamydia Infections) : Knockdown of CHOP in U937 cells significantly reduced the synergistic effects of TLR and ER stress on IL-23p19 expression, but did not affect expression of other LPS-responsive genes
Song et al., Leukemia 2011 : LBH589 also significantly repressed the production of interleukin (IL)-6, IL-10, IL-12p70, IL-23 and tumor necrosis factor-a by Toll-like receptor (TLR)3 and TLR4 induced DC activation, indicating an important role of HDAC activity in immune regulation and inflammation
Kwok et al., Arthritis Res Ther 2012 (Sjogren's Syndrome) : The stimulation of TLR2, TLR4 and TLR6 additively induced the production of IL-17 and IL-23 from the PBMCs of pSS patients especially in the presence of TLR2 stimulation
Zaal et al., Immunobiology 2013 : While C5a indeed enhanced cytokine production of immature DCs, the addition of C5a inhibited production of IL-12, IL-23 and TNFa induced by various TLR ligands such as LPS, R848 and Pam ( 3 ) CSK ( 4 )
den Dunnen et al., Blood 2012 (Bacterial Infections...) : First, TLR-Fc?RIIa costimulation strongly increased transcription of pro-IL-1ß and IL-23p19
McBerry et al., J Immunol 2012 (Disease Models, Animal...) : p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed TLR induced IL-12/23p40 production
Perugorria et al., Hepatology 2013 (Liver Cirrhosis...) : KCs lacking Tpl2 display defects with TLR induction of cytokines interleukin (IL)-1ß, IL-10, and IL-23
Compté et al., PloS one 2013 : The aim of our study was to define the relative contribution of age and clinical status on TLR induced interleukin (IL)-12p70 and IL-23 production as these cytokines play an important role in the protection against intracellular and extracellular pathogens, respectively
Callahan et al., J Immunol 2013 (Disease Susceptibility...) : ABIN-1-deficient DCs display exaggerated NF-?B and MAPK signaling and produce more IL-23 than do normal cells in response to TLR ligands
Ma et al., PloS one 2013 : In this study, our data suggest that Tim-3 and IL-12/IL-23 gene transcriptions are regulated by enhanced or silenced Gal-9 expression within monocytes through synergizing with TLR signaling